Compare gastric sleeve/bypass surgery with GLP-1 medications like Ozempic, Wegovy, and Mounjaro. Get evidence-based insights on effectiveness, cost, and long-term results.
Should I choose surgery or medication for weight loss?
Surgery (gastric sleeve/bypass) delivers 60-80% excess weight loss that's maintained long-term for $15,000-$30,000 one-time cost. GLP-1 medications (Ozempic, Wegovy) deliver 15-20% weight loss while taking them, costing $400-$600/month ongoing. Weight typically returns when medication stops.
| Factor | Surgery (Gastric Sleeve/Bypass) | GLP-1 Medication (Ozempic/Wegovy) |
|---|---|---|
| Weight Loss | 60-80% of excess weight | 15-20% of total weight |
| Timeline | 12-18 months to goal | 12-18 months while taking |
| Duration | Permanent tool | Must continue indefinitely |
| Cost (1 Year) | $15,000-$30,000 (one-time) | $4,800-$7,200 (ongoing) |
| Cost (5 Years) | ~$20,000 total (incl. vitamins) | $24,000-$36,000 |
| Medicare Rebate | Yes ($1,500-$2,500) | No (not PBS listed for obesity) |
| Insurance Coverage | Yes (with waiting period) | Rarely covered |
| Invasiveness | Surgical procedure | Weekly/monthly injection |
| Recovery | 2-4 weeks off work | No downtime |
| Side Effects | Surgical risks (2-3%) | Nausea, vomiting (30-40%) |
| Diabetes Remission | 60-90% | Improves but rarely cures |
| Weight Regain Risk | 15-20% regain some weight | Most regain when stopping |
| Best For | BMI 35+, severe obesity | BMI 27-35, mild to moderate |
According to OSSANZ data, gastric sleeve delivers 60-70% excess weight loss, gastric bypass 70-80%. Results maintained long-term in 70-80% of patients at 5 years.
Example:
Starting: 120kg (target 70kg, excess 50kg)
After surgery: Lose 30-40kg
End weight: 80-90kg
Clinical trials show 15-20% total body weight loss while taking medication. Weight typically returns to 60-70% of what was lost within 1 year of stopping.
Example:
Starting: 120kg
While taking: Lose 18-24kg
End weight: 96-102kg
Stop meds: Regain 11-17kg
Cost Crossover Point:
Surgery becomes more cost-effective after approximately 2-3 years of medication use.
All information is based on Australian clinical guidelines, government health resources, and peer-reviewed medical research.
Primary Clinical Sources:
Supporting Research:
Additional data from peer-reviewed journals including Obesity Surgery, JAMA Surgery, The Lancet, and publications indexed in PubMed and Cochrane Library databases.
Medical Disclaimer: This information is for educational purposes only and does not constitute medical advice. Always consult with qualified, AHPRA-registered healthcare professionals before making decisions about weight loss surgery. Individual results may vary based on personal health factors and adherence to post-surgical protocols.
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